Page 23 - Envision-09-10-2021
P. 23

HYLO-DUAL                                                                         ALL-ROUND
                                          ®
                                                                                                   THE


                                                                                                DROP

           DRY EYE AND ALLERGY RELIEF                                                          FOR BOTH
                                                                                            DRY EYES AND
           PRESERVATIVE FREE | PHOSPHATE FREE | TOP GERMAN TECHNOLOGY
                                                                                               ALLERGIES










          Dry eye: a vicious cycle of tear film
          instability and hyperosmolarity,
          leading to inflammation and discomfort 1






















                                     The ALL-ROUND DROP                                        PROVEN
                                     combines the POWER of:
                                                                                              ALLERGY
                                     ECTOINE                                                    RELIEF
                                     a natural osmoprotectant                                     +

                                       Prevents cell dehydration 2,3
                                       Stabilizes the lipid layer of the tear film            POWERFUL
                                       preventing excessive tear evaporation 4             HYDRATION
                                       Reduces inflammation and allergy symptoms 8,9      &PROTECTION
                                                                                             FOR DRY EYES
                                     SODIUM HYALURONATE
                                     a water-retaining polysaccharide
                                       Long-lasting hydration and lubrication  10,11
                                       Beneficial in restoring the osmotic balance 5
                                       Improvement of dry eye symptoms 11

                                                      TM           © 2021 CANDORVISION (a division of Candorpharm Inc.)
                                                                   CP 23073 Montreal, Canada H4A 1T0 Tel.: 514-380-5270
                                                                   candorvision.com


           1.  Craig JP, et al., TFOS DEWS II Report Executive Summary, The Ocular Surface (2017), http://dx.doi.org/10.1016/j.jtos.2017.08.003; 2. M. Dwivedi, et al., Biophysical investigations of the structure and function of the tear fluid lipid layer and the effect of ectoine. Part A: Natural meibomian
           lipid films, Biochim. Biophys. Acta (2014), http://dx.doi.org/10.1016/j.bbamem.2014.05.011; 3. Kempf B, Bremer E. Uptake and synthesis of compatible solutes as microbial stress responses to high-osmolality environments. Arch Microbiol 1998;170:319-30. PMID: 9818351; 4. Harishchandra RK,
           Wulff S, Lentzen G, Neuhaus T, Galla HJ. The effect of compatible solute ectoines on the structural organization of lipid monolayer and bilayer membranes. Biophys Chem. 2010;150(1–3):37–46. doi: 10.1016/j.bpc.2010.02.007; 5. Aragona P, Di Stefano G, Ferreri F, Spinella R, Stilo A. Sodium
           hyaluronate eye drops of different osmolarity for the treatment of dry eye in Sjögren’s syndrome patients. Br J Ophthalmol. 2002;86:879–884; 6. Jiang T, Jiang J, Zhou Y, Zhao G, Yang S, Li H, et al. Application of sodium hyaluronate to the operation of suturing the corneal perforation. Int J Ophthalmol.   F-HD-OSMO2-EN
           2010;3(3):269-71; 7. Yang G, Espandar L, Mamalis N, Prestwich G. A cross-linked hyaluronan gel accelerates healing of corneal epithelial abrasion and alkali burn injuries in rabbits. Vet Ophthalmol. 2010;13(3):144-50; 8. Peuschel H, Sydlik U, Haendeler J, Büchner N, Stöckmann D, Kroker M, et al.
           c- Src-mediated activation of Erk1/2 is a reaction of epithelial cells to carbon nanoparticle treatment and may be a target for a molecular preventive strategy. Biol Chem. 2010;391(11):1327-32; 9. Research C. A double-blind, randomized, cross-over study of the effects of Ectoin® allergy nasal spray and
           Ectoin® allergy eye drops compared to placebo, in patients with allergic rhinitis and allergic conjunctivitis in an environmental exposure chamber (EEC) model. Mississauga, Ontario, Canada; 2010. 10. Snibson GR, et al. Ocular Surface Residence Times of Artificial Tear Solutions. Cornea. 1992; 11(4):
           288-293; 11. Jones L. et al. TFOS DEWS II – Management and Therapy. Ocul Surf. 2017; 15(3):575-628. Data on file.
   18   19   20   21   22   23   24   25   26   27   28