Page 7 - Envision - May June 2020
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Hylo-Dual_EN_2020_ENVISION_MAY-JUNE.pdf   2   2020-04-27   9:36 AM
       HYLO-DUAL                                                                               ALL-ROUND
                                                                                                      THE

                                                                                                    DROP


        DRY EYE AND ALLERGY RELIEF                                                                FOR BOTH
                                                                                               DRY EYES AND
        PRESERVATIVE FREE | PHOSPHATE FREE | TOP GERMAN TECHNOLOGY                                ALLERGIES






                            Our entire team is here for you!
             Working remotely, we are continuing operations and provide
            support to optometrists and patients during usual business hours
                        Monday to Friday, 9 a.m. to 5 p.m. EST.


                        In these challenging times, stay healthy,
                          positive and don’t forget your eyes!

                          EVERYTHING WILL BE ALRIGHT!


 C
 M
 Y
 CM
 MY
 CY
 CMY
                                    The ALL-ROUND DROP
 K
                                    combines the POWER of:

                                    ECTOINE
                                    a natural osmoprotectant                                     PROVEN
                                                                                               ALLERGY
                                       Prevents cell dehydration 2,3                             RELIEF
                                       Stabilizes the lipid layer of the tear film
                                       preventing excessive tear evaporation 4                      +
                                       Reduces inflammation and allergy symptoms 8,9
                                                                                                POWERFUL
                                    SODIUM HYALURONATE
                                    a water-retaining polysaccharide                        HYDRATION
                                                                                           &PROTECTION
                                       Long-lasting hydration and lubrication  10,11
                                       Beneficial in restoring the osmotic balance 5          FOR DRY EYES
                                       Improvement of dry eye symptoms 11


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         1.  Craig JP, et al., TFOS DEWS II Report Executive Summary, The Ocular Surface (2017), http://dx.doi.org/10.1016/j.jtos.2017.08.003; 2. M. Dwivedi, et al., Biophysical investigations of the structure and function of the tear fluid lipid layer and the effect of ectoine. Part A: Natural meibomian
         lipid films, Biochim. Biophys. Acta (2014), http://dx.doi.org/10.1016/j.bbamem.2014.05.011; 3. Kempf B, Bremer E. Uptake and synthesis of compatible solutes as microbial stress responses to high-osmolality environments. Arch Microbiol 1998;170:319-30. PMID: 9818351; 4. Harishchandra RK,
         Wulff S, Lentzen G, Neuhaus T, Galla HJ. The effect of compatible solute ectoines on the structural organization of lipid monolayer and bilayer membranes. Biophys Chem. 2010;150(1–3):37–46. doi: 10.1016/j.bpc.2010.02.007; 5. Aragona P, Di Stefano G, Ferreri F, Spinella R, Stilo A. Sodium   F-HD-OSMO2-EN
         hyaluronate eye drops of different osmolarity for the treatment of dry eye in Sjögren’s syndrome patients. Br J Ophthalmol. 2002;86:879–884; 6. Jiang T, Jiang J, Zhou Y, Zhao G, Yang S, Li H, et al. Application of sodium hyaluronate to the operation of suturing the corneal perforation. Int J Ophthalmol.
         2010;3(3):269-71; 7. Yang G, Espandar L, Mamalis N, Prestwich G. A cross-linked hyaluronan gel accelerates healing of corneal epithelial abrasion and alkali burn injuries in rabbits. Vet Ophthalmol. 2010;13(3):144-50; 8. Peuschel H, Sydlik U, Haendeler J, Büchner N, Stöckmann D, Kroker M, et al.
         c- Src-mediated activation of Erk1/2 is a reaction of epithelial cells to carbon nanoparticle treatment and may be a target for a molecular preventive strategy. Biol Chem. 2010;391(11):1327-32; 9. Research C. A double-blind, randomized, cross-over study of the effects of Ectoin® allergy nasal spray and
         Ectoin® allergy eye drops compared to placebo, in patients with allergic rhinitis and allergic conjunctivitis in an environmental exposure chamber (EEC) model. Mississauga, Ontario, Canada; 2010. 10. Snibson GR, et al. Ocular Surface Residence Times of Artificial Tear Solutions. Cornea. 1992; 11(4):
         288-293; 11. Jones L. et al. TFOS DEWS II – Management and Therapy. Ocul Surf. 2017; 15(3):575-628. Data on file.
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