Page 14 - Envision-05-2022

Cover Story

T HE P R E SB Y OP I A OP P OR T UNI T Y

PRESBYOPIA-CORRECTING EYE DROPS
“ The perfect management tool could be the other hand, purport to restore
The newest game-changing presbyopia 2. Lens restoration eye drops, on
pharmaceutical agents - miotic-based
accommodation at the root of
presbyopia-correcting and lens-restoration eye drops. The presbyopia by softening the lens
eye drop should perfect presbyopia-correcting eye proteins (Novartis - Dioptin) to
provide improvement in drop should provide improvement in restore elasticity or by stabilizing
a range of uncorrected vision at near
lens
protein
(Viewpoint
the
a range of with minimal compromise to distance Therapeutics VP1-001) to prevent
uncorrected vision at vision and restore accommodation. stiffening.
The drop should also be comfortable
near with minimal on instillation, fast-acting and Presbyopia-correcting eye drops are
compromise to long-lasting with excellent safety and not to be taken as an absolute
replacement for reading glasses,
minimal adverse effect profiles.
distance vision contact lenses or surgery but as a
and restore 1. Miotic-based drops allow the pupil supplement to these and other
“ a pinhole effect that increases the there are nine presbyopia-correcting
or aperture to constrict and create modalities. At the time of writing,
accommodation.
eye’s depth of focus. AGN-190584 eye drop solutions in various phases
(Vuity: 1.25% Pilocarpine HCl) by of clinical trials (Table 1) and many
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Allergan, an AbbVie company, has are expected to receive regulatory
already been approved and is on the approval in the near future. For the
market. millions of presbyopes in Canada
and the U.S., the prospect of a new
treatment strategy is most welcome
news.

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12 / MAY - JUNE 2022 / www.ENVISIONMAGAZINE.ca /